Metabolism of zearalenone in female rat liver in vitro
نویسندگان
چکیده
منابع مشابه
Imatinib metabolism and disposition in isolated rat perfused liver
Imatinib is an orally administered tyrosine kinase inhibitor which inhibits the Bcr-Abl protein-tyrosine kinase with high selectivity. Imatinib is rapidly absorbed from the gut, after oral intake and has an almost absolute bioavailability of 98%. The metabolism of imatinib is mediated by the cytochrome P450 (CYP) isoenzymes in the liver and gut wall. CGP74588 is a major active metabolite of ima...
متن کاملMetabolism in vitro of 19-nortestosterone in female rat liver homogenate.
A study ilz viva of 19-nortestosterone metabolism in the postmenopausal woman has revealed a metabolic pattern of products similar to that obtained after the administration of testosterone (1). In the present investigation the transformation of 19-nortestosterone by female rat liver homogenates was studied. The rate of reduction of ring A by this tissue system appeared to be extremely rapid. Fo...
متن کاملIn vitro metabolism of hyperforin in rat liver microsomal systems.
Hyperforin is an important active component of St. John's wort (Hypericum perforatum) that has been suggested to be responsible for the St. John's wort antidepressive effects and herbal-drug interactions. In this study, the in vitro metabolism profile of hyperforin was investigated using liver microsomes from male and female Sprague-Dawley rats, with or without induction by phenobarbital or dex...
متن کاملimatinib metabolism and disposition in isolated rat perfused liver
imatinib is an orally administered tyrosine kinase inhibitor which inhibits the bcr-abl protein-tyrosine kinase with high selectivity. imatinib is rapidly absorbed from the gut, after oral intake and has an almost absolute bioavailability of 98%. the metabolism of imatinib is mediated by the cytochrome p450 (cyp) isoenzymes in the liver and gut wall. cgp74588 is a major active metabolite of ima...
متن کاملthe effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mycotoxins
سال: 1980
ISSN: 0285-1466,1881-0128
DOI: 10.2520/myco1975.1980.11_37